Cardiovascular / Circulatory Support (CVS) and Cardiovascular Hemodynamics

  1. Problem: Cardiovascular (CVS) dysfunction is a leading cause of death and managing the circulation and support is largely done clinically using intuition and experience . The main problem is that there are no means of providing real-time diagnosis of emerging dysfunction or poor circulation dynamics and thus no way to effectively guide therapy.
  2. Solution: A patient-specific model of CVS and circulation would provide real-time monitoring and diagnosis to better guide therapy and patient care
  3. Current Research Status: the UC and ULG teams have developed unique, clinically validated models of the cardiovascular system in critical illness . These models are based on extensive ULG animal study and physiology data. Both are creating novel methods to identify these models and make them patient specific. This work requires more research investment in modeling and animal trials to prove the concept before testing in humans
  4. Goal: A proven computer model of the heart and circulation that can be used to diagnose CVS dysfunction and guide therapy.
  5. Major Research Tasks:
  • Exchange modeling and computational technology between UC and ULG
  • Develop animal trials to generate data sets that can be used to prove the models and methods ability to diagnose accurately a range of CVS dysfunction
  • Test and optimise results in clinical trials in EU and NZ to prove the concept.

Related eTime results on the Publications page!